These are the characters that didn't make to the ending of the stories.
- Rameses: gets swept away by the Red Sea being rearranged.
- General Mandible: gets killed by falling to his death on a root.
- Tzekel Kan: arrested by Cortes' men for trying to lead them to El Dorado, only to find it was blocked.
- Cortes: Leaves with his men having not found El Dorado.
- Mrs. Tweedy: gets tricked by Ginger into cutting the rope, making her fall down and into the pie machine. She gets stuck. Then, she is defeated by her husband, Mr. Tweedy who shuts the door on her.
- Mr. Tweedy: reforms and becomes a protagonist.
- Lord Farquaad: gets eaten alive by the dragon.
- Fairy GodMother: explodes into bubbles.
- Don Lino: reforms and becomes a protagonist.
- Frankie: Dies after an anchor lands on him while chasing Oscar.
- Lola: goes to ask Oscar for forgiveness only for Crazy Joe to show up instead. She is implied to forcibly date him.
- The fossa: gets chased off by Alex.
- Vincent, Gladys and Dwayne: get exterminated by the de pelter turbo then Vincent sent to the Rocky Mountains while Gladys and Dwayne get arrested.
- The Toad: gets his tongue stuck with his french cousin, Le Frog.
- Spike and Whitey: Reform and Become portagonists.
- Prince Charming: Celebrates "Livin' La Vida Loca" in the 2nd film then gets killed by the fake castle, pushed by the dragon in the third film.
- Dr. Layton T. Montgomery: gets sued.
- Tai Lung: gets Defeated by Po, after Po lets go of his Wuxi Finger Hold Tai Lung Vanished into a Golden Wave of energy rippling across the Landscape.
- Makunga: gets tricked by Alex into getting defeat by Nana.
- Gallaxhar: gets Killed By Explosion Of His Ship.
- Rumpelstiltskin: gets caged.
- Tighten: gets defeated by Megamind then arrested.
- Lord Shen: gets killed by the ruined cannon and then explosion death.
- Jack and Jill: go in the hospital After Being Attacked by the Great Terror.
- Captitaine Chantel DuBois and her men: get shipped in crates headed for Madagascar.
- Pitch: gets taken down by his own fear.