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Here are the cast in Dog-Man: The Second Epic Movie:

Dog-Man - Frank Welker

Chief - Danny DeVito

Petey the Cat - Seth MacFarlane

Lil Petey - Brooklyn Prince

Petey's Father - Sean Cullen (same voice as Old Rick from Cloudy With a Chance of Meatballs)

Sarah Hatoff - Margot Robbie

Yolay Caprese - Amy Adams

Big Jim - Brad Garrett

Dr. Scum - Rainn Wilson

Piggy - Jordan Peele (same voice as Melvin Sneedly from Captain Underpants: The First Epic Movie)

Crunky - Bill Fagerbakke

Bub - Steve Buscemi

Daryl - Sean Hayes

Uncle Larry - Kevin James

George Beard - Kevin Hart

Harold Hutchins - Thomas Middleditch

Jessica Gordon - Isabela Moner

Sophie "Sophie One/Permanent Sophie" Gordon - Addison Holley

Sophie "Other Sophie/Temporary Sophie" Evans - Chloe Lourenco Lang

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